One-step Micro-Albumin Rapid Urine Test Kits

Micro Albumin Test strip and cassette

Micro Albumin urine test kit is a chromatographic immunoassay for the semi-quantitative detection of micro-albumin in human urine specimen based on competitive inhibition principle. The test result can be used in many clinical diagnostic situations, especially as a prognostic marker of kidney damages in its early stage.

Principle of HSA Rapid Test Strip and Cassette

After added to the membrane of the test strip or cassette, the urine specimen will dissolve the pre-coated micro-albumin-specific monoclonal antibody labeled with colloidal gold. The micro-albumin, if present in the urine specimen, will react with the colloidal gold conjugated antibody on the nitrocellulose filter. If there is enough micro albumins in the urine, all the colloidal gold conjugated antibody will be bound, leaving no or very small amount of colloidal gold conjugated antibody to react with the micro albumin pre-coated in the test (T) region. So, no colloidal gold particle will be bound in the test region, and no colored line appears, indicating a strong positive result (>50mg/L).

If the albumin concentration in the specimen is not high enough, and there are some colloidal gold conjugated antibody left to be bound in the test region, a dim pink line will develop in the test region, indicating the concentration is higher than normal value 20mg/L, but lower than 50 mg/L. And, if test line is as dark as, or darker than, the reference line, it means the concentration is normal (<20 mg/L).

This albumin-antibody colloidal gold complex will be caught by the pre-coated goat anti-mouse IgG antibody (secondary antibody), and pink lines will develop, indicating the correctness of the assay. In this way, the control line acts as an inside control measure.

Micro-Albumin and Human Health

When there is an abnormally high permeability for albumin in the renal glomerulus, microalbumin in the blood will leak into the urine, and that will cause the so called microalbuminuria. The level of albumin produced by microalbuminuria is lower than that can be detected by urine reagent strips. Usually, when the level is above 100 mg/L, it is considered serious microalbuminuria; when it is over 300 ml/L, it is then called macroalbuminuria or albuminuria. The level of micro albumin can be used in many situations in clinical diagnosis realm, among them including: as an indicator of subclinical cardiovascular disease; as a marker of vascular endothelial dysfunction; as an important prognostic marker for kidney disease, such as diabetes mellitus and hypertension; and, as a risk factor for venous thromboembolism.

MiA Urine Rapid Test Kits

No.Cat. No.Description
(Click For Details)
SpecimenPCS/BoxQuan. per CTN Quantity Interested* Add to
Inquiry
1 MiA 151 Micro-Albumin Urine Test Strip urine 100 Bulk: 6000 PCS
Boxed: 48 Boxes
PCS
2 MiA 152 Micro-Albumin Urine Test Cassette urine 25 Bulk: 1600 PCS
Boxed: 40 Boxes
PCS
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Micro Albumin test strip and cassette
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