T.cruzi IgG Rapid Test Cassette for Chagas Diagnosis

Chagas Test Kit

The Trypanosoma cruzi IgG Chagas Rapid Test Cassette is a lateral flow chromatographic immunoassay for the qualitative detection of IgG antibody to the T. cruzi in human serum, plasma or whole blood. It is intended to be used as a screening test and as an aid in the diagnosis of infection with T. cruzi infection. This T. Cruzi IgG Rapid Test cassette is an instant IgG antibody test, which detects IgG antibodies to the T. cruzi within 15 minutes without any instrument requirements. T. cruzi specific recombinant antigens are adopted, which enables our test kit to detect the T.Cruzi antibodies with high sensitivity and specificity.

Principle

The Chagas IgG Rapid Test is based on the principle of indirect immunoassay. The test cassette consists of: 1) a burgundy colored conjugate pad containing Protein A conjugated with colloid gold (Protein A conjugates), 2) a nitrocellulose membrane strip containing a test band (T band) and a control band (C band). The T band is pre-coated with recombinant T. cruzi antigens, and the C band is pre-coated with anti-Protein A antibodies.

When an adequate volume of test specimen is dispensed into the sample well of the test cassette, the specimen migrates by capillary action across the cassette. The IgG antibodies to T. cruzi, if present in the specimen, will bind to the Protein A conjugates. The immunocomplex is then captured on the membrane by the pre-coated T. cruzi antigens, forming a burgundy colored T band, indicating a Chagas Ab positive test result. Absence of the T band suggests a negative result.

Background Information

Trypanosoma cruzi is a species of parasitic euglenoids. The trypanosomes characteristically bore tissue in human tissue and primarily feed on blood and also lymph. This behaviour causes the disease of trypanosomiasis in humans, usually known as American trypanosomiasis or Chagas Disease, which causes a systemic infection of humans with acute manifestations and long term sequelae. Early infections are treatable with the medication benznidazole or nifurtimox. Medication nearly always results in a cure if given early, but becomes less effective the longer a person has had Chagas disease. When used in chronic disease, medication may only delay or prevent the development of end-stage symptoms. Early diagnosis is helpful to reduce the bad effect of this disease. It is estimated that 16-18 million individuals are infected worldwidely, and roughly 50,000 people die each year from chronic Chagas disease (World Health Organization), and it is significantly serious in Latin America.

T.cruzi IgG Chagas Rapid test cassette

No.Cat. No.Description
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1 CHAG 411 T.cruzi IgG Chagas Test cassette serum/WB/plasma 25 Bulk: 1600 PCS
Boxed: 40 Boxes
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T.cruzi IgG Chagas rapid test cassette
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