T.Cruzi IgG Rapid Test
T.Cruzi IgG test cassette is rapid immunoassay, intended to be used to detect the infection of Trypanosoma Cruzi virus, as an aid in the diagnosis of Chagas disease.
The Trypanosoma cruzi IgG Chagas Rapid Test Cassette is a lateral flow chromatographic immunoassay for the qualitative detection of IgG antibody to the T.Cruzi virus in human serum, plasma or whole blood. It is intended to be used as a screening test and as an aid in the diagnosis of infection with T. cruzi infection.
This T. Cruzi Chagas IgG Rapid Test cassette is an instant IgG antibody test, which detects IgG antibodies to the T. cruzi within 15 minutes without any extra instrument. T. cruzi specific recombinant antigens are adopted, which enables our test kit to detect the T.Cruzi antibodies with high sensitivity and specificity.
T.Cruzi IgG Rapid Test Principle
The Chagas IgG Rapid Test is based on the principle of indirect immunoassay. The test cassette consists of: 1) a colored conjugate pad containing Protein A conjugated with colloid gold, 2) a nitrocellulose membrane strip containing a test band (T band) and a control band (C band). The T band is pre-coated with recombinant T.Cruzi antigens, and the C band is pre-coated with anti-protein A antibodies.
When an adequate volume of test specimen is added to the sample well, the IgG antibodies to T.Cruzi, if present in the specimen, will bind to the Protein A conjugates. The immunocomplex is then captured on the membrane by the pre-coated T.Cruzi antigen when the compounds moves along the strip under the capillary effect, forming a burgundy colored T band, indicating Chagas IgG positive.
Trypanosoma cruzi is a species of parasitic euglenoids. The trypanosomes characteristically bore the human tissues and primarily feed on blood and lymph. This behaviour causes the disease of trypanosomiasis in humans, known as American trypanosomiasis or Chagas Disease, which causes a systemic infection with acute manifestations and long term sequelae, even death.
Early infections are treatable with the medication benznidazole or nifurtimox. Medication nearly always results in a cure if given in early stage, but becomes the less effective the later the treatment is administered. So, early diagnosis is helpful to reduce the bad effect of this disease.