Enterovirus 71 IgM Immunoassay Test Kits

Enterovirus 71 Test kit

EV-71 IgM DOT ELISA, EV-71 IgM ELISA and EV-71 IgM Dot Filtration Test Kits are used for the qualitative determination of IgM-class antibodies to human enterovirus-71 (EV71) in serum or plasma samples. These EV-71 Immunoassay kits are intended to be used in clinical laboratories for early diagnosis and management of patients infected with Enterovirus 71, a.k.a. the 'hand-foot-mouth disease (HFMD)'.

Enterovirus 71 Dot Assay Kit and Dot-ELISA kit are easy to use, and no other reagent or equipment is needed during the assay procedures, so they can used in the field as Point-of-Care Test (POCT) kits; While Enterovirus ELISA kit are suitable to screen large quantity of blood specimens especially when the hand-foot-mouth disease is epidemic in a certain region.

Immunoassay Principle

These rapid test kits are both used as a quick POCT HFMD test kits for the diagnosis of the 'hand-foot-mouth disease'. The principles of the EV71 DOT filtration test kit and EV71 DOT ELISA kit are similar. Antibodies directed to human immunoglobulin M proteins (anti-μ chain) are pre-coated on the microwell or nitrocellulose membrane, which will capture the IgM antibodies (the target of the assay) after serum is added. If these complexes develop, it will capture the monoclonal anti-EV71 antibodies conjugated to the enzyme horseradish peroxidase (HRP-conjugate) in the subsequent process. The bound HRP will make the subsequently added colorless chromogens to develop blue color under hydrolyzing effect, indicating a positive result. The color intensity is proportional to the amount of antibody in the sample.

The principles of the EV71 ELISA kit and EV71 DOT ELISA kit are similar. Antibodies directed to human immunoglobulin M proteins (anti-μ chain) are pre-coated on the microwell or nitrocellulose membrane, which will capture the IgM antibodies (the target of the assay) after serum is added. If these complexes develop, it will capture the monoclonal anti-EV71 antibodies conjugated to the enzyme horseradish peroxidase (HRP-conjugate) in the subsequent process. The bound HRP will make the subsequently added colorless chromogens to develop blue color under hydrolyzing effect, indicating a positive result. The color intensity is proportional to the amount of antibody in the sample.

Human Enterovirus 71 and HFMD

Human Enterovirus 71 (EV71), the newly detected member of Enterovirudae, is notable for its etiological role in epidemics of severe neurological diseases in children. The illness usually peaks in June or July. EV71 infection may be asymptomatic or may cause diarrhea and rashes. EV71 one of the major causative agents for 'hand-foot-mouth disease (HFMD)', is sometimes associated with severe central nervous system diseases. Direct detection of virus is the mainstay of diagnosis. EV 71 can be isolated from throat and stool specimens, as well as from skin vesicle fluid. EV 71-specifc serological assays, including rapid test, ELSIA and DOT ELISA kits specific for IgM antibody, have also been developed to assist for early and easier diagnosis of the HFMD disease.

Enterovirus 71 IgM Immunoassay Test Kits

No.Cat. No.Description
(Click For Details)
SpecimenPCS/BoxQuan. per CTN Quantity Interested* Add to
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1 EV71 911 Enterovirus 71 IgM Rapid Cassette serum/WB/plasma 25 Bulk: 1600 PCS
Boxed: 40 Boxes
PCS
2 EV71 9113 Enterovirus 71 IgM Dot ELISA serum/plasma 24T/48T Bulk: 42 PCS
Boxed: 42 Boxes
boxes
3 EV71 9114 Enterovirus 71 IgM ELISA Kit serum/plasma 48/96T Boxed: 40 Kits boxes
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  2. EV71 IgM Dot immunossay kit, Dot ELISA kit and ELIA kit are available,
Enterovirus 71 IgM Test Kit
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