TB Test Kits
TB Correlative IFN-γ Release Assay (TB-IGRA) and traditional TB rapid test kits are supplied.
TB Rapid Test Kits
Tuberculosis rapid test cassette, also called one-step TB test kit, is a lateral flow chromatographic immunoassay (CIA) kit; and TB Dot assay kit is an immuno dot filtration assay kit; both of these POCT test kits are for the direct qualitative detection of tuberculosis antibodies in human serum or plasma specimen.
These TB rapid test kits are widely used as an aid in the diagnosis of infection due to Mycobacterium tuberculosis, because they are easy to perform, and takes as short as minutes to get the testing results, instead of waiting for days for the testing result with other complicated testing methods.
TB Correlative IFN-γ Release Assay (TB-IGRA)
TB-IGRA is an ELISA kit for the quantitative detection (2~400pg/ml) of Interferon Gamma (IFN-y) that respond to in-vitro stimulation by Mycobacterium tuberculosis antigens in human whole blood. It is intended for use as an aid in the diagnosis of tuberculosis (TB) infection, including both latent tuberculosis infection (LTBI) and tuberculosis (TB) disease.
Merits of TB-IGRA ELISA kit
IGRA measures a person's immune reactivity to M.tuberculosis. When infected with Mycobacterium tuberculosis, specific T-lymphocytes will appear in the blood of the patient, which will be stimulated to proliferate and release cytokines such as IFN-γ, when they are mixed with antigens derived from M.Tuberculosis. The concentration of IFN-γ is positively related with the quantity of tuberculosis antigens.
The antigens selected for stimulation is specific fragments that pathogenic Mycobacterium tuberculosis contains, while BCG vaccine and other Mycobacterium don't contain. This greatly improves the specificity of the TB-IGRA Assay kit. And this
TB Assay kit is easier to operate than PCR, bacterial culture and SPOT. And this TB-IGRA ELISA kit can be used in the following realms:
- Active tuberculosis detection;
- Latent tuberculosis detection;
- TB therapeutic effect monitor;
- Medication instruction;
- Prevent TB cross infection.
Tuberculosis is a highly infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis (MTB or TB). It is a small bacillus that can withstand weak disinfectants and can survive in a dry state for weeks. TB is transmitted almost exclusively by aerosol from the respiratory secretions of patients with active M. tuberculosis.
Most of the infected will keep asymptomatic, and about 10% progress to active disease. Tuberculosis mainly affects the lungs and about 80% of all cases of tuberculosis were limited to the lungs. Extra-pulmonary cases most happen to immunosuppressed patients. It was reported that half of the patients can be killed by the TB infection, if not treated with antibiotics. Morbidity of tuberculosis has been decreasing, but recently HIV–associated tuberculosis and multi-drug resistant tuberculosis are on the rise. Persons with silicosis have an approximately 30-fold greater risk for TB infection.
As present, Tuberculosis remains an important socio-economical and medical problem throughout the world. The early detection of tuberculosis disease will help to reduce and chance of further spread, and will help to the cure of the infected. In this way, the IVD Tuberculosis (TB) testing devices are contributing to the control of tuberculosis disease.