Measles IgG & Measles IgM POCT Dot Assay Kits

Measles IGG & Measles IGM POCT Dot Assay Kits

Measles IgG Dot assay Kit and Measles IgM Dot assay Kit are immunoassay kits based on the Dot Immuno Gold Filtration Assay (DIGFA) principle, which are intended to be used to detect respectively the IgG and IgM antibody to Morbilli virus in human serum or plasma specimen, as an aid in the diagnosis of Measles infection.

Although for clinical diagnosis of measles, the specific symptoms such as measles rash can be used to help reach a clinical conclusion, especial when the disease is epidemic in a region, the laboratory diagnosis of IgG and IgM antibodies to measles virus can be of great help in the diagnosis process.

When the measles IgM antibody is detected in a patient's blood, it is a strong indicator of measles infection; while a positive result of Measles IgG test result may indicate the past infection, or the immunity status to this disease.

Principle

In these measles antibody test kits, purified measles antigen is used as capturer, which is pre-coated on the nitrocellulose membrane of the dot assay cassette. A second antibody, i.e. anti-human IgG or IgM antibodies labeled with colloidal gold particle is used as detector. When the target IgG or IgM antibody presents in the specimen added, the antigen-antibody-secondary antibody complex will be formed. With the accumulation of colloidal gold particles which is colored, some visual line will develop in the test line region, indicating a positive result.

Background of Measles Infection

Measles, also known as rubeola or morbilli, is an infection of the respiratory system caused by a Morbillivirus, which is enveloped, single-stranded, negative-sense RNA virus. Measles is spread through respiration contact with fluids from an infected person's nose and mouth, either directly or through aerosol droplets transmission. Morbillivirus is highly contagious, and studies show that 90% of people without immunity who shares living space with an infected person will be infected. The incubation period is about 14 days, and infectivity lasts from 2-4 days prior, until 2-5 days after the onset of the rash.

The typical symptoms of measles include four day of fever, the three Cs, i.e. cough, coryza (runny nose) and conjunctivitis (red eyes). Koplik spots seen inside the mouth are pathognomonic for measles, but they are transient and may disappear within the day of arising. The measles rash appears two to four days after initial symptoms and lasts for up to eight days. It starts on the head, and then spread to cover most of the body, often causing itching. Complications of measles are relatively common, including mild diarrhea, pneumonia, ear infections, bronchitis, and acute encephalitis.

There is only one measles virus serotype, and the antigenicity is the same, so people who had suffered from measles generally has the immunity to it all the life. Measles is an endemic disease. In populations that have not been exposed to measles, exposure to measles as a new disease can be devastating. According to WHO, measles is a leading cause of vaccine-preventable childhood mortality.

Measles IgG & Measles IgM POCT Dot Assay Kits

No.Cat. No.Description
(Click For Details)
SpecimenPCS/BoxQuan. per CTN Quantity Interested* Add to
Inquiry
1 MV 8512 Measles Virus IgM Dot Assay serum 25 Bulk: 1200 PCS
Boxed: 36 Boxes
PCS
2 MV 8522 Measles Virus IgG Dot Assay serum 25 Bulk: 1200 PCS
Boxed: 36 Boxes
PCS
NOTES:
  1. Please put the items of interest into the "Inquiry Cart" by entering a quantity & clicking "ADD"; and then Check & Send the inquiry by clicking the Icon of Inquiry Cart.
H.pylori Rapid Test Kit
Atlas Link products