ssDNA IgG Antibody Dot Filtration Assay Kit

ssDNA IgG Dot Assay Cassette

ssDNA IgG Dot filtration test kit is an immunoassay based on the principle of Gold Filtration immune Assay principle, intended for the qualitative detection of IgG antibody specific to Single-Strand DNA (ss-DNA) in human serum, and intended to be used as an aid in the diagnosis of Rheumatoid Arthritis.

ssDNA Antibody and Rheumatoid Arthritis

Serological changes have been found in connection with SLE. Antibodies specific to DNA belong to the group of anti-nuclear antibodies (ANA), which occur in several autoimmune diseases. Antibodies to double-stranded DNA (dsDNA) are specific to SLE. But antibodies to single-stranded DNA (ssDNA) also have a correlation with the SLE cased. The ssDNA is found with a frequency of up to 87% during acute phases and 43% during inactive phases in patients with SLE. But ssDNA is not specific for SLE as they may be found in other diseases, including infectious mononucleosis (40%), autoimmune hepatitis (58%), acute myeloid leukemia (89%), acute lymphatic leukemia, chronic myeloid leukemia (60%) and juvenile rheumatoid arthritis (35-50%). SLE-like symptoms may be induced by drugs, too. As anti-ssDNA antibodies are found with a frequency of up to 50% in patients with a drug-induced SLE. The determination of antibodies against ssDNA, together with other test such as dsDNA testing, may be helpful for the differential diagnosis.

Systemic lupus erythematosus (SLE) is an autoimmune disease, in which the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. Heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system are the usually affected organs. It is a Type III hypersensitivity reaction caused by antibody-immune complex formation. This disease believed to be genetic, and may be triggered by factors such as chronic drug treatment, certain virus, and emotional press.

ssDNA IgG Antibody Dot Assay Kit

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1 ssDNA R722 Single Stranded DNA IgG Dot Assay serum 25 Bulk: 1200 PCS
Boxed: 36 Boxes
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