FOB and FOB-TRF Test Kits
Atlas Link Technology Co., Ltd supplies a series of FOB rapid test kits, used as an aid in the diagnosis of gastrointestinal disorders; TRF is a better tumor marker test for the upper gastrointestinal tract, while FOB for lower tract.
FOB and FOB-TRF Rapid Test Kits
FOB Rapid Test kits and FOB-TRF Rapid test kits, are a fast and visual immune-chromatographic testing devices for the qualitative detection of blood hemoglobin (Fecal Occult Blood, i.e. FOB) in human fecal specimens. These fecal occult blood rapid test kits come in strip and cassette format, and are intended to be used as an aid in the diagnosis of lower gastrointestinal (g.i.) disorders, such as colorectal cancers and adenomas. In this regard, the FOB and FOT-TRF test kits are usually referred to as cancer test device.
While One-Step FOB-TRF Combo Test is an antigen-capture immunochromatographic assay, detecting the presence of transferrin and fecal occult blood in one single fecal sample. Monoclonal antibodies specifically against human transferrin and hemoglobin, respectively, are 1) conjugated with colloidal gold and deposited on the conjugate pad, and 2) immobilized on the Test Zone (2 and 1) on the nitrocellulose membrane.
When a fecal extraction sample is added, it rehydrates the gold-antibody conjugate and the transferrin and/or hemoglobin, if any in samples, interact with the colloidal gold conjugated antibodies. The antigen-antibody-colloidal gold complex will migrate towards the test window until the Test Zone (2 and 1) where they are captured by immobilized antibodies, forming a visible pink line (indicate positive results). If transferrin and hemoglobin is absent in the sample, no pink line will appear in the Test Zone (2 and 1), indicate negative results.
Why FOB Testing Matters
With our FOB tumor marker rapid test kit, the occult blood can be detected at as low concentration as 40 ng/ml. Since the earlier the diseases like bowel cancer are diagnosed, the better the chance of a cure, an early detection of the FOB in faeces is very important to the treatment of many digestive system disorders. Because usually a cost of a rapid FOB testing kit is almost neglectable, it is highly advisable that the people vulnerable to the related diseases have a screening test regularly.
FOB and TRF: Background information
Fecal occult blood (FOB)refers to the small amount blood in the human faeces, which is not visually detectable. There are several human body disorders which may cause bleeding into the intestines. Ulcers, colitis, polyps, and bowel cancer are the most common ones. In the early stages, cancers in digestive system often cause slight bleeding into the gut, which are often neglected because there are no symptoms at these stages.
Transferrin (TRF) is a blood plasma protein for iron ion delivery. A patient with an increased serum transferrin level often suffers from iron deficiency anemia that is one of the most important symptoms when a tumor has caused chronic occult bleeding.
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